diff --git a/lldb/test/API/functionalities/ptr_refs/TestPtrRefs.py b/lldb/test/API/functionalities/ptr_refs/TestPtrRefs.py
index 7e3b7dfb7752..e945688cbe3f 100644
--- a/lldb/test/API/functionalities/ptr_refs/TestPtrRefs.py
+++ b/lldb/test/API/functionalities/ptr_refs/TestPtrRefs.py
@@ -14,6 +14,7 @@ class TestPtrRefs(TestBase):
     mydir = TestBase.compute_mydir(__file__)
 
     @skipUnlessDarwin
+    @expectedFailureAll(oslist=["macosx"], debug_info=["dwarf", "gmodules"], bugnumber="llvm.org/pr45112")
     def test_ptr_refs(self):
         """Test format string functionality."""
         self.build()
diff --git a/lldb/test/API/lang/objc/ptr_refs/TestPtrRefsObjC.py b/lldb/test/API/lang/objc/ptr_refs/TestPtrRefsObjC.py
index 41a063b4ab99..f8b6db1a7a5e 100644
--- a/lldb/test/API/lang/objc/ptr_refs/TestPtrRefsObjC.py
+++ b/lldb/test/API/lang/objc/ptr_refs/TestPtrRefsObjC.py
@@ -14,6 +14,7 @@ class TestPtrRefsObjC(TestBase):
     mydir = TestBase.compute_mydir(__file__)
 
     @skipUnlessDarwin
+    @expectedFailureAll(oslist=["macosx"], debug_info=["dwarf", "gmodules"], bugnumber="llvm.org/pr45112")
     def test_ptr_refs(self):
         """Test the ptr_refs tool on Darwin with Objective-C"""
         self.build()