diff --git a/llvm/lib/Target/Mips/AsmParser/MipsAsmParser.cpp b/llvm/lib/Target/Mips/AsmParser/MipsAsmParser.cpp
index 5b5bbe2fd52e..7d02c542de42 100644
--- a/llvm/lib/Target/Mips/AsmParser/MipsAsmParser.cpp
+++ b/llvm/lib/Target/Mips/AsmParser/MipsAsmParser.cpp
@@ -3781,12 +3781,20 @@ bool MipsAsmParser::parseDirectiveCPSetup() {
   if (!eatComma("unexpected token, expected comma"))
     return true;
 
-  StringRef Name;
-  if (Parser.parseIdentifier(Name))
-    reportParseError("expected identifier");
-  MCSymbol *Sym = getContext().GetOrCreateSymbol(Name);
+  const MCExpr *Expr;
+  if (Parser.parseExpression(Expr)) {
+    reportParseError("expected expression");
+    return false;
+  }
 
-  getTargetStreamer().emitDirectiveCpsetup(FuncReg, Save, *Sym, SaveIsReg);
+  if (Expr->getKind() != MCExpr::SymbolRef) {
+    reportParseError("expected symbol");
+    return false;
+  }
+  const MCSymbolRefExpr *Ref = static_cast<const MCSymbolRefExpr *>(Expr);
+
+  getTargetStreamer().emitDirectiveCpsetup(FuncReg, Save, Ref->getSymbol(),
+                                           SaveIsReg);
   return false;
 }
 
diff --git a/llvm/lib/Target/Mips/MCTargetDesc/MipsTargetStreamer.cpp b/llvm/lib/Target/Mips/MCTargetDesc/MipsTargetStreamer.cpp
index 357f7a4229c5..a329234fb214 100644
--- a/llvm/lib/Target/Mips/MCTargetDesc/MipsTargetStreamer.cpp
+++ b/llvm/lib/Target/Mips/MCTargetDesc/MipsTargetStreamer.cpp
@@ -706,9 +706,10 @@ void MipsTargetELFStreamer::emitDirectiveCpsetup(unsigned RegNo,
   Inst.clear();
 
   const MCSymbolRefExpr *HiExpr = MCSymbolRefExpr::Create(
-      Sym.getName(), MCSymbolRefExpr::VK_Mips_GPOFF_HI, MCA.getContext());
+      &Sym, MCSymbolRefExpr::VK_Mips_GPOFF_HI, MCA.getContext());
   const MCSymbolRefExpr *LoExpr = MCSymbolRefExpr::Create(
-      Sym.getName(), MCSymbolRefExpr::VK_Mips_GPOFF_LO, MCA.getContext());
+      &Sym, MCSymbolRefExpr::VK_Mips_GPOFF_LO, MCA.getContext());
+
   // lui $gp, %hi(%neg(%gp_rel(funcSym)))
   Inst.setOpcode(Mips::LUi);
   Inst.addOperand(MCOperand::CreateReg(Mips::GP));
diff --git a/llvm/test/MC/Mips/cpsetup-bad.s b/llvm/test/MC/Mips/cpsetup-bad.s
index 09252a1310ed..ec6525a195f1 100644
--- a/llvm/test/MC/Mips/cpsetup-bad.s
+++ b/llvm/test/MC/Mips/cpsetup-bad.s
@@ -12,3 +12,11 @@ t1:
 # ASM: :[[@LINE-1]]:23: error: expected save register or stack offset
         .cpsetup $31, $32, __cerror
 # ASM: :[[@LINE-1]]:23: error: invalid register
+        .cpsetup $25, $2, $3
+# ASM: :[[@LINE-1]]:28: error: expected expression
+        .cpsetup $25, $2, 4
+# ASM: :[[@LINE-1]]:28: error: expected symbol
+        .cpsetup $25, $2, 4+65
+# ASM: :[[@LINE-1]]:31: error: expected symbol
+        .cpsetup $25, $2, foo+4
+# ASM: :[[@LINE-1]]:32: error: expected symbol
diff --git a/llvm/test/MC/Mips/cpsetup.s b/llvm/test/MC/Mips/cpsetup.s
index 9b5f6b62ef99..a3ffae67aaec 100644
--- a/llvm/test/MC/Mips/cpsetup.s
+++ b/llvm/test/MC/Mips/cpsetup.s
@@ -6,14 +6,14 @@
 # RUN:   FileCheck -check-prefix=ASM %s
 
 # RUN: llvm-mc -triple mips64-unknown-unknown -target-abi n32 -filetype=obj -o - %s | \
-# RUN:   llvm-objdump -d -r -arch=mips64 - | \
+# RUN:   llvm-objdump -d -r -t -arch=mips64 - | \
 # RUN:     FileCheck -check-prefix=NXX -check-prefix=N32 %s
 
 # RUN: llvm-mc -triple mips64-unknown-unknown -target-abi n32 %s | \
 # RUN:   FileCheck -check-prefix=ASM %s
 
 # RUN: llvm-mc -triple mips64-unknown-unknown %s -filetype=obj -o - | \
-# RUN:   llvm-objdump -d -r -arch=mips64 - | \
+# RUN:   llvm-objdump -d -r -t -arch=mips64 - | \
 # RUN:     FileCheck -check-prefix=NXX -check-prefix=N64 %s
 
 # RUN: llvm-mc -triple mips64-unknown-unknown %s | \
@@ -61,6 +61,35 @@ t2:
 
 # ASM: .cpsetup $25, $2, __cerror
 
+# .cpsetup with local labels (PR22518):
+1:
+        .cpsetup $25, $2, 1b
+        nop
+        sub $3, $3, $2
+        nop
+
+# O32: t2:
+# O32:   nop
+# O32:   sub $3, $3, $2
+# O32:   nop
+
+# FIXME: Direct object emission for N32 is still under development.
+# N32 doesn't allow 3 operations to be specified in the same relocation
+# record like N64 does.
+
+# NXX: move     $2, $gp
+# NXX: lui      $gp, 0
+# NXX: R_MIPS_GPREL16/R_MIPS_SUB/R_MIPS_HI16  $tmp0
+# NXX: addiu    $gp, $gp, 0
+# NXX: R_MIPS_GPREL16/R_MIPS_SUB/R_MIPS_LO16  $tmp0
+# N32: addu     $gp, $gp, $25
+# N64: daddu    $gp, $gp, $25
+# NXX: nop
+# NXX: sub $3, $3, $2
+# NXX: nop
+
+# ASM: .cpsetup $25, $2, $tmp0
+
 t3:
         .option pic0
         nop
@@ -76,3 +105,7 @@ t3:
 # ASM: nop
 # ASM: .cpsetup $25, 8, __cerror
 # ASM: nop
+
+# For .cpsetup with local labels, we need to check if $tmp0 is in the symbol
+# table:
+# NXX: .text  00000000 $tmp0