The program Flexbar preprocesses high-throughput sequencing data
efficiently. It demultiplexes barcoded runs and removes adapter
sequences. Moreover, trimming and filtering features are provided.
Flexbar increases read mapping rates and improves genome as well as
transcriptome assemblies. It supports next-generation sequencing data
in fasta and fastq format, e.g. from Roche 454 and the Illumina
platform.
The script downloads the segan-library needed for compilation.
References
Johannes T. Roehr, Christoph Dieterich, Knut Reinert:
Flexbar 3.0 - SIMD and multicore parallelization. Bioinformatics 2017.
Matthias Dodt, Johannes T. Roehr, Rina Ahmed, Christoph Dieterich:
Flexbar - flexible barcode and adapter processing for next-generation
sequencing platforms. Biology 2012.
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